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An in silico approach for the antigenic mutation and immune memory. Authorship: CASTRO, A. de; FRONZA, C. F.; ALVES, D. The this article we studied in machina an approach to simulate the process of antigenic mutation. Our results have suggested that the durability of the immune memory is affected by process of antigeni... ... Repository: BDPA Publication year: 2009
Memory immune responses and protection of chickens against a nephropathogenic infectious bronchitis virus strain by combining live heterologous and inactivated homologous vaccines. Authorship: SANTOS, R. M. dos; FERNANDO, F. S.; MONTASSIER, M. de F. S.; SILVA, K. R.; LOEPS, P. D.; PAVANI, C.; BORZI, M. M.; OKINO, C. H.; MONTASSIER, H. J. In this study, we evaluated antibody and cell-mediated immune (CMI) responses in the mucosal and systemic compartments and protection against challenge with a nephropathogenic Brazilian (BR-I) strain... ... Repository: BDPA Publication year: 2019
In silico approach for viral mutations and sustainability of immunizations. Authorship: CASTRO, A. de In this paper we use virtual samples of individuals and a dynamical modeling proposed in a previous study to study the behavior of immune memory against antigenic mutation. Repository: BDPA Publication year: 2015
Computational approach of the homeostatic turnover of memory B cells. Authorship: CASTRO, A. de; FRONZA, C. F.; ANSELMO, J. In this paper, a discrete mathematical model inspired by control mechanisms is used to explore the factors potentially responsible for maximum immunization capacity in mammals. The results have been d... ... Repository: BDPA Publication year: 2014
Um modelo computacional para estudar a influência dos anticorpos na manutenção da memória imunológica. Authorship: CASTRO, A. de; FRONZA, C. F.; GIACHETTO, P. F.; ALVES, D. Este artigo apresenta um modelo computacional para estudar a evolução temporal do repertório clonal, incluindo populações de anticorpos. O modelo proposto também foi utilizado para estudar o comportam... ... Repository: BDPA Publication year: 2009
A polyvalent virosomal infuenza vaccine induces broad cellular and humoral immunity in pigs. Authorship: HAACH, V.; BASTOS, A. P. A.; GAVA, D.; FONSECA, F. M. da; MORES, M. A. Z.; COLDEBELLA, A.; FRANCO, A. C.; SCHAEFER, R. Abstract: Background: Influenza A virus (IAV) is endemic in pigs globally and co-circulation of genetically and antigenically diverse virus lineages of subtypes H1N1, H1N2 and H3N2 is a challenge for... ... Repository: BDPA Publication year: 2023
Mechanisms of resistance and tolerance against parasites in fish: the impairments caused by Neoechinorhynchus buttnerae in Colossoma macropomum. Authorship: BILLER, J. D.; CHAGAS, E. C. Tambaqui is the second native fi sh most produced species in Brazil. Currently, tambaqui fi sh farms deals with serious sanitary problems due to the prevalence of the parasite Neoechinorhynchus buttne... ... Repository: BDPA Publication year: 2022
Uma aplicação da abordagem de Verhulst para investigar a influência da mutação antigênica na durabilidade da memória imune. Authorship: CASTRO, A. de Modelos matemáticos têm sido utilizados para responder a várias questões imunológicas complexas como o processo de memória imunológica e a duração de vacinas, onde os mecanismos de regulação ainda não... ... Repository: BDPA Publication year: 2010
Gene expression of Toll-Like 2 and 4 receptors and T gama delta WC1 cells receptors related to the levels of infection in cattles naturally infected by agents of tick-borne diseases. Authorship: GOMES, H. C. S. F.; OKINO, C. H.; TONELLI, M. F.; OLIVEIRA, M. C. de S.; OLIVEIRA, H. N. DE Bovine babesiosis is an infectious disease caused by protozoa Babesia bovis and B. bigemina, intraerythrocyte parasites that produce intravascular hemolytic anemia. Repository: BDPA Publication year: 2021
Primary and secondary mucosal immunity after challenge with Brazilian avian infectious bronchitis variant. Authorship: OKINO, C. H.; MORES, M. A. Z.; MONTASSIER, H. J.; MATTOS, G. L. M.; BRENTANO, L.; COLDEBELLA, A.; RITTERBUSCH, G. A.; ESTEVES, P. A.; TREVISOL, I. M. Repository: BDPA Publication year: 2014

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