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Repressive epigenetic mechanisms, such as the H3K27me3 histone modification, were predicted to affect muscle gene expression and its mineral content in Nelore cattle. Authorship: AFONSO, J.; SHIM, W. J.; BODEN, M.; FORTES, M. R. S.; DINIZ, W. J. da S.; LIMA, A. O. de; ROCHA, M. I. P.; CARDOSO, T. F.; BRUSCADIN, J. J.; GROMBONI, C. F.; NOGUEIRA, A. R. A.; MOURÃO, G. B.; ZERLOTINI NETO, A.; COUTINHO, L. L.; REGITANO, L. C. de A. Abstract. Epigenetic repression has been linked to the regulation of different cell states. In this study, we focus on the influence of this repression, mainly by H3K27me3, over gene expression in mus... ... Repository: BDPA Publication year: 2023
DNA methylation may affect beef tenderness through signal transduction in Bos indicus. Authorship: SOUZA, M. M. de; NICIURA, S. C. M.; ROCHA, M. I. P.; PAN, Z.; ZHOU, H.; BRUSCADIN, J. J.; DINIZ, W. J. da S.; AFONSO, J.; OLIVEIRA, P. S. N. de; MOURÃO, G. B.; ZERLOTINI NETO, A.; COUTINHO, L. L.; KOLTES, J. E.; REGITANO, L. C. de A. Abstract. Background:Beef tenderness is a complex trait of economic importance for the beef industry. Understanding the epigenetic mechanisms underlying this trait may help improve the accuracy of bre... ... Repository: BDPA Publication year: 2022
Muscle allele-specific expression QTLs may affect meat quality traits in Bos indicus. Authorship: BRUSCADIN, J. J.; SOUZA, M. M. de; OLIVEIRA, K. S. de; ROCHA, M. I. P.; AFONSO, J.; CARDOSO, T. F.; ZERLOTINI NETO, A.; COUTINHO, L. L.; NICIURA, S. C. M.; REGITANO, L. C. de A. Abstract. Single nucleotide polymorphisms (SNPs) located in transcript sequences showing allele-specific expression (ASE SNPs) were previously identified in the Longissimus thoracis muscle of a Nelore... ... Repository: BDPA Publication year: 2021
Allele-specific expression is widespread in Bos indicus muscle and affects meat quality candidate genes. Authorship: SOUZA, M. M. de; ZERLOTINI NETO, A.; ROCHA, M. I. P.; BRUSCADIN, J. J.; DINIZ, W. J. da S.; CARDOSO, T. F.; CESAR, A. S. M.; AFONSO, J.; ANDRADE, B. G. N.; MUDADU, M. de A.; MOKRY, F. B.; TIZIOTO, P. C.; OLIVEIRA, P. S. N. de; NICIURA, S. C. M.; COUTINHO, L. L.; REGITANO, L. C. de A. Differences between the expression of the two alleles of a gene are known as allele-specific expression (ASE), a common event in the transcriptome of mammals. Despite ASE being a source of phenotypic... ... Repository: BDPA Publication year: 2020
Muscle transcriptome analysis reveals genes and metabolic pathways related to mineral concentration in Bos indicus. Authorship: AFONSO, J.; COUTINHO, L. L.; TIZIOTO, P. C.; DINIZ, W. J. da S.; LIMA, A. O. de; ROCHA, M. I. P.; BUSS, C, E.; ANDRADE, B. G. N. A.; PIAYA. O.; SILVA, J. V.; LINS, L. A.; GROMBONI, C. F.; NOGUEIRA, A. R. de A.; FORTES, M. R. S.; MOURÃO, G. B.; REGITANO, L. C. de A. Mineral content affects the biological processes underlying beef quality. Muscle mineral concentration depends not only on intake-outtake balance and muscle type, but also on age, environment, breed,... ... Repository: BDPA Publication year: 2019
Genome-wide distribution of allele-specific expression in Nelore steers muscle. Authorship: SOUZA, M. M.; ZERLOTINI NETO, A.; NICIURA, S. C. M.; ROCHA, M. I. P.; DINIZ, W. J.; TIZIOTO, P. C.; OLIVEIRA, P. S. N.; LIMA, A. O.; AFONSO, J.; CESAR, A. S. M; COUTINHO, L. L.; REGITANO, L. C. de A. Summary. The difference between the allelic expression of a gene is known as allele-specific expression (ASE), and it is a common event in mammal?s transcriptome. ASE is named genomic imprinting when... ... Repository: BDPA Publication year: 2018
LDHB gene has allele-specific expression in liver of Nelore cattle extremes for feed efficiency. Authorship: ROCHA, M. I. P.; SOUZA, M. M. de; ZERLOTINI NETO, A.; TIZIOTO, P. C.; OLIVEIRA, P. S. N. de; LIMA, A. O. de; AFONSO, J.; DINIZ, W. J. da S.; BUSS, C. E.; COUTINHO, L. L.; REGITANO, L. C. de A.; NICIURA, S. C. M. Feed efficiency is a multi-factorial trait of a large economic importance for cattle. Although previous studies reported gene expression differences associated with this trait the contribution of alle... ... Repository: BDPA Publication year: 2017
Putative genes involved in muscle functioning are differentially expressed in Nelore steers divergent for sodium and potassium concentration. Authorship: AFONSO, J.; LINS, L. A.; CASSARO, E. G.; TIZIOTO, P. C.; OLIVEIRA, P. S. N. de O.; DINIZ, W. J. da S.; LIMA, A. O. de; SOUZA, M. M. de; ROCHA, M. I. P.; SILVA, J. V. da; BUSS, C. E.; GROMBONI, C. F.; MOURAO, G. B.; NOGUEIRA, A. R. de A.; COUTINHO, L. L.; REGITANO, L. C. de A. Repository: BDPA Publication year: 2017
Potential regulatory elements on PCDH7 gene affecting residual feed intake in Nelore cattle. Authorship: LIMA, A. O. de; TIZIOTO, P. C.; OLIVEIRA, P. S. N. de; GEISTLINGER, L.; ROCHA, M. I. P.; DINIZ, W. J. da S.; AFONSO, J.; BUSS, C. E.; PETRINI, J.; MOURAO, G. B.; COUTINHO, L. L.; REGITANO, L. C. de A. Repository: BDPA Publication year: 2017
Identification of a pleiotropic locus for beef quality and feed efficiency in cattle using bi-trait genome-wide association analysis. Authorship: BUSS, C. E.; PETRINI, J.; MOURAO, G. B.; GEISTLINGER, L.; WOLF, J. B.; DINIZ, W. J. da S.; ROCHA, M. I. P.; AFONSO, J.; LIMA, A. O. de; TIZIOTO, P. C.; TULLIO, R. R.; ANDRADE, B. G.; COUTINHO, L. L.; REGITANO, L. C. de A. Repository: BDPA Publication year: 2017

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